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Preethi Bala Balakrishnan
Senior Scientist Ii - Translational Immunology Pre-clinical Pharmacology @Arsenal Biosciences, Inc.
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WORK HISTORY
Senior Scientist Ii - Translational Immunology Pre-clinical Pharmacology @Arsenal Biosciences, Inc.
South San Francisco, CA, US
EDUCATION
Harvard University
Master's Thesis Project, Tissue Engineering
Shanmugha Arts, Science, Technology and Research Academy
Bachelor of Technology (BTech), Bioengineering and Biomedical Engineering
Massachusetts Institute of Technology
Master's project in Harvard MIT Health science and Technology Program (HST), Tissue engineering and micro fabrication technology
Shanmugha Arts, Science, Technology and Research Academy
Master of Technology (MTech), Medical Nanotechnology
University of Genoa
Doctor of Philosophy - PhD (incollaboration with Italian Institure of technology), Nanochemistry
SKILLS
ABOUT PREETHI BALA BALAKRISHNAN
I am a self-motivated and innovative scientist with 10 years of research experience in the areas of oncology, immunology, infectious diseases, translational biology, and nanotechnology. I am organized, detail and goal-oriented, fast-learner with training from top universities around the world. I enjoy working in independent/collaborative, fast-paced, and high-functioning environment. My project management skills and ability to handle multiple projects simultaneously have resulted in many successful high impact international peer-reviewed publications.To pursue my goals for a successful career in translational science, help move groundbreaking medical technologies to patients in need, I have gained experience in testing various therapeutics like small molecule drugs, antibodies, ADC, immunomodulatory agents, cell-based products, nanoparticle formulations and imaging probes targeting cancers and infectious diseases, throughout my PhD, postdoctoral and biotech industrial trainings. Technical skills: Handling human blood; isolation of PBMCs; isolation, culture, characterization, and analysis of human immune cells from PBMCs and tumors; Isolation, culture, characterization of immune cells from mouse spleen, lymph node, bone marrow and tumors; animal handling (IV, IP, SQ, IM, IT injections); multi-color flow cytometry; Luminex cytokine analysis; ELISA; ELISpot; cytotoxicity assays, IC50, LD50, EC50 determination, dose response studies; metabolic assays – ATP, LDH, lactate, glucose, ALT/AST, MTS, MTT, Seahorse (OCR, ECAR) assay; western blot, SDS-PAGE; microscopy techniques; viral handling, HIV handling, neutralization assays, killing assay; Synthesis of inorganic nanoparticle, polymer coating, immunomodulator conjugation and/or encapsulation on/in nanoparticles, stability assay, payload release studies; Small animals imaging using IVIS, LagoX, PET/CT scanner, MPI. Other skills: Writing manuscripts and protocols, data and statistical analysis and interpretation, detailed record keeping, report writing, due diligence, leadership/mentorship experience, technology transfer, IACUC (animal care and use) protocol manager, financial stewardess (ordering and communications with vendors), technical software like GraphPad, FlowJo, ImageJ, Biorender, presentation and communication skills.
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