Jianhui

WORK HISTORY

EDUCATION

ABOUT JIANHUI

M.D. and Ph.D. in molecular biology and cell biology with 12+ years of academic research experience and expertise in cancer cell biology, cell cycle, DNA-Damage repair, synthetic lethality, E3 ligases and innate immunology, supported by a strong publication record in top-tier journals• 6 years of industry experience in oncology drug development, from early discovery through IND, and translational-clinical stage with extensive experience in small molecule drug discovery, including PROTAC/degrader, and deep understanding of diverse modalities, including antibody drug conjugates (ADCs), radioligand therapy (RLT), T-cell engagers (TCEs) and monoclonal/bispecific antibodies• Expertise in designing and executing preclinical studies for drug screening, evaluating efficacy, PK/PD, MOA, predict optimal human dose/exposure, novel combinations and biomarker hypotheses• Translational scientist with strong expertise in integrating novel therapies, identifying novel biomarkers, combinations and target indications, and developing clinical biomarker strategies to drive drug development.• Expertise in development, implementation of clinical biomarker strategies, authoring and review of regulatory documents (IND, IB, ODD, FDA meeting packages) and clinical study protocols and reports.• Experience in managing internal teams and external collaborators and CROs, as well as maintaining collaborations with cross functional teams and key opinion leaders, to advance drug development programs• Highly reliable and driven, with exceptional time management and prioritization skills, consistently delivering results in fast-paced environments.