Daniel Joseph Oconnell
Vice President Head of Biology @Quotient Therapeutics
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WORK HISTORY
Vice President Head of Biology @Quotient Therapeutics
Cambridge, MA, US
Leading the biology strategy at Quotient Therapeutics, where we leverage functional genomics, high-throughput perturbation, and screening to explore and directly test hypotheses in disease-relevant models. Our mission is to translate somatic genomics discoveries into validated therapeutic targets by integrating cutting edge genetic tools with relevant biological systems. Our platform technology is an interconnected web that links functional validation and therapeutic development directly to our somatic genomics discovery engine, enabling continuous data-driven iteration of transformative medicines for patients in need.
EDUCATION
Harvard Medical School
Doctor of Philosophy (Ph.D.), Genetics
Cornell University
Bachelor of Science (B.Sc.), Biological Sciences
SKILLS
ABOUT DANIEL JOSEPH OCONNELL
Experienced leader in genomics, computational biology, and human genetics, with a proven ability to build and lead interdisciplinary teams to drive data-driven drug discovery and translational medicine. Expertise in biomarker discovery, multi-omics integration, and AI/ML-driven computational approaches to accelerate target identification. Extensive experience in regulatory interactions for genome editing, AAV, and RNA-based therapeutics, with successful IND and CTA filings across hematopoietic stem cells, TCR-T cells, and in vivo gene editing programs. Adept at fostering collaboration across matrixed teams, integrating cutting-edge computational and experimental approaches to advance therapeutic programs. Committed to leveraging human genetics, functional genomics, and computational science to translate targets and technologies into transformative therapies.
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