Brett Howell
Senior Director of QSP, CPMS Oncology, GSK
- Role
- Senior Director, Qsp, Cpms Oncology at GSK
- Location
- Salisbury, NC, US
- LinkedIn followers
- 500 followers
About Brett Howell
I currently serve in the role of Senior Director of QSP at GSK within the CPMS Oncology group. My role is to apply QSP to help advance drug development programs and contribute to new cancer treatments.I served as President of QSP Solutions at Simulations Plus Inc. from 2017 to 2024. Simulations Plus works to provide the pharmaceutical industry with in silico software and consulting solutions related to chemical design, drug exposure, safety, and efficacy. My business unit was focused on quantitative systems pharmacology (QSP) and toxicology (QST) modeling to enable therapeutic development. We specialized in oncology, autoimmune disease, fibrosis, complement, liver disease, lung disease, safety, and much more.My educational background and training is in chemical engineering and PBPK/QSP modeling.
Experience
Senior Director, Qsp, Cpms Oncology
Sep 2025 — Present · Charlotte, NC, US
As Senior Director of QSP within CPMS oncology at GSK, I focus on leading a team that is applying quantitative systems pharmacology (QSP) and toxicology (QST) solutions to address key clinical drug development questions, and to facilitate the advancement and approval of new medicines for cancer patients.
Education
University of Florida
Doctor of Philosophy, Chemical Engineering
2006 — 2010
North Carolina State University
Bachelors of Science, Chemical Engineering, Textile Engineering
2002 — 2006
Skills
- R
- Pharmacokinetics
- Pharmacodynamics
- Modeling and Simulation
- Jmp
- Fluorescence Spectroscopy
- Systems Biology
- Matlab
- Chemical Engineering
- Maple
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