Subramanya Srikantan
Sr Principal Scientist @Regeneron
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WORK HISTORY
Sr Principal Scientist @Regeneron
Tarrytown, NY, US
Lead a multidisciplinary team of scientists responsible for cell based assay development, advanced cell line engineering, and CRISPR/Cas9-based gene editing.• Oversaw the management of a cell line inventory exceeding several thousand unique models, enabling broad discovery and therapeutic testing initiatives.• Directed efforts to deorphanize critical cell surface receptors and secreted proteins, creating new therapeutic opportunities across oncology, neurodegeneration, and metabolic disease.• Championed the integration of automation and machine learning into scientific workflows, enhancing scalability, efficiency, and reproducibility of research.• Guided the development of novel bioassays (flow binding, cytotoxicity, and functional kill assays) that accelerated therapeutic screening and candidate prioritization.• Fostered a culture of innovation and accountability, mentoring associates in best practices and positioning them for growth.
EDUCATION
University of Mysore
Masters, Microbiology
Government Science college/Bangalore University
Bachelor of Science (B.Sc.), Chemistry, Zoology & Microbiology
Centre for Celluar and Molecular Biology
Ph.D., Cell and Molecular Biology
SKILLS
ABOUT SUBRAMANYA SRIKANTAN
Executive leader and Ph.D. scientist with deep expertise in biotechnology and life sciences, specializing in cell line engineering, assay development, and translational research. I bring a proven track record of leading diverse, high-performing scientific teams to deliver innovation at scale — from advancing CRISPR/Cas9-based gene editing to pioneering bioassays that accelerate therapeutic discovery.I am recognized for bridging technical depth with strategic foresight, spearheading initiatives that deorphanize critical therapeutic targets, integrate automation and machine learning into research workflows, and drive cross-functional collaborations that shape the future of drug discovery.As a leader, I focus on cultivating innovation, mentoring the next generation of scientists, and securing resources through strategic grantsmanship and partnerships. With a strong foundation in molecular mechanisms of aging, cancer, and neurodegenerative diseases, I am committed to transforming complex science into actionable solutions that create impact for patients, organizations, and society.
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