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Ryan Stansfield

Director @858 Therapeutics

San Diego, CA, US
EMAILS
r••••••••@8five8tx.com
MOBILE NUMBERS
+16•••••••97

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WORK HISTORY

Nov 2022 — Present

Director @858 Therapeutics

San Diego, CA, US

Effectively managed lead program’s 28-day GLP IND-enabling toxicology studies including genetic toxicology and safety pharmacology studies•Authored all ADME, toxicology, and select pharmacology non-clinical reports for a successful IND submission•Built out DMPK laboratory to enable the internal analysis of PK/TK samples, perform in vitro ADME assessment studies, and formulate test article for in vivo studies•Led DMPK/toxicology group including recruitment, mentorship, and development of a high-performing team of scientists and management of budget and timelines•Oversaw ADME, safety pharmacology, and toxicology preclinical activities to ensure timely and rigorous data enabling a positive IND submission•Collaborated with regulatory, CMC, and clinical team to develop strategy for on-going clinical development activities•Evaluated new targets and in-licensing opportunities as part of the executive diligence team to support expansion of portfolio

EDUCATION

1993 — 1997

UC Santa Barbara

B.S., Zoology

SKILLS

CROOncologyChemistryClinical DevelopmentProtein ChemistryCancer ResearchMass SpectrometryBiochemistryLc-MsDrug DiscoveryPharmaceutical IndustryGlpWinnonlinR&DHigh Throughput ScreeningPharmacokineticsHplcCRO ManagementDrug DevelopmentCancerBioanalysisChromatographyDmpk

ABOUT RYAN STANSFIELD

Innovative and analytical scientist with experience in small molecule drug discovery and development. Proven track record of success with 7 programs progressing from discovery to clinical trials. Hands-on, in depth expertise in ADME, safety pharmacology, and toxicology. Excellent communicator, well organized, and efficient problem solver.

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