Rajan C.

WORK HISTORY

EDUCATION

SKILLS

ABOUT RAJAN C.

9+ years of proven track record in computational method development, protein structure modeling, ligand-based and structure-based drug design projects with provisional patent and publications.* Collaborated with chemists and biologists on variety of drug discovery projects covering targets such as GLP1R, CHD1, Caspase3, eIF4A, AXL, PD1, PDL1, EphB4, CCR4, ETBR, Integrins and modalities such as small molecules, peptides, lasso peptides, macrocyclic compounds, cyclic peptides and DNA/RNA aptamers that resulted in hit identification, lead optimizations, SAR/mechanism understandings and high impact publications.* In-depth experience in handling software such as Schrodinger, MOE, Open Eye, Rosetta, Modeller and PyMOL.* Expertise in applying statistical and machine learning techniques for cheminformatics projects.* Adept at planning, developing and maintaining cheminformatics pipeline/workflows.* Experience in handling large data such as NCBI, PubChem, ChEMBL, TCGA, CCLE, ZINC and PubMed.* Strong programming skills in Python, R, Perl, HTML, PHP, SQL, Javascript and Ajax.* Hands on experience with cloud services including AWS, Azure and Google Colab.* 4+ years of experience in maintaining HPC clusters and IT infrastructure for computational chemistry core/labs.* Proficient in wet lab techniques such as mammalian cell culture, transfection and cell-based assays.* Excellent oral and written communications skills with publications and presentations.* Demonstrated leadership, organizational and project management skills.