Matt Casey
Global Head of Execution Systems @CSL
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WORK HISTORY
Global Head of Execution Systems @CSL
King of Prussia, PA, US
Lead global Operational Technology organization across 9 international sites, supporting critical operations such as blood plasma fractionation, bulk purification, cell culture, parenteral fill & finish, and packaging- Provide functional leadership for Automation (DCS/PCS), Manufacturing Execution Systems (MES), Computer Systems Validation (CSV), Process Operations & Technology (Including Data Systems), and Laboratory Execution Systems- Defined and implemented a global Operational Technology strategy focused on reducing technical debt, accelerating digital innovation, and delivering scalable solutions that enhance business value and optimize business processes- Harmonized PCS/MES platforms across business units, consolidating vendors and standardizing architecture to improve compliance and scalability- Partnered with IT, Quality, Engineering and Manufacturing leadership to establish global OT governance for digital manufacturing initiatives.
EDUCATION
Drexel University
Chemical Engineering
SKILLS
ABOUT MATT CASEY
Accomplished biotech and pharmaceutical engineering leader with 20+ years of expertise across drug substance and drug product development, manufacturing operations, tech transfer, operational technology, and facility commissioning and qualification in both large and small molecule platforms. Recognized for leading cross-functional global teams, fostering innovation and collaboration, driving strategic digital transformation, and delivering complex capital projects with operational excellence.
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