Jason Oneill
Director, Protein Chemistry @Omeros Corporation
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WORK HISTORY
Director, Protein Chemistry @Omeros Corporation
Seattle, WA, US
EDUCATION
UC San Diego
BS, Biology
University of Washington
PhD, Protein Biochemistry, X-ray Crystallography
SKILLS
ABOUT JASON ONEILL
Director, Protein Sciences. Protein Engineering & Therapeutic DiscoveryProtein science leader with 20 years of experience in biotechnology, specializing in structure-based engineering of therapeutic modalities. Proven track record on directing cross-functional teams and integrating technical strategies towards the advancment of protein biologics through discovery and early process development.Protein Engineering & ProductionExpert in research-scale purification process development and analytical characterization of preclinical biologics. Skilled in building high-throughput, small- and mid-scale platforms for protein and antibody (Ab) purification. Leverage deep expertise in protein structure and modeling to accelerate development of therapeutic proteins and diverse Ab formats. Extensive experience with bioconjugation strategies, supporting ADC and peptide/protein conjugate programs.Technical Project ManagementDeep understanding of early discovery and lead optimization, including modality selection, manufacturability, and potency. Strong grounding in disease biology enables effective collaboration with multidisciplinary teams to identify therapeutic paths and nominate lead candidates. Known for aligning technical execution with program goals to drive advancement of preclinical assets.
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