Bernardino Ossola
Head of Disease Biology - Neuroscience (Director) @Cerevance
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WORK HISTORY
Head of Disease Biology - Neuroscience (Director) @Cerevance
Cambridge, GB
Leading technical teams in biological validation of novel targets for neurodegenerative diseases (PD, AD, ALS, FTD)• Assess clinical feasibility with focus on translatable target-engagement biomarkers• Develop and validate in-vitro assays with complex, disease-relevant systems• Identify and outsource suitable in-vivo proof-of-concept/efficacy studiesManaging multiple projects from Hit Finding to Lead Optimization and non-GLP tox• Matrix-manage cross-functional in-vitro/in-vivo pharmacology, MedChem and DMPK teams• Provide strategic input on timelines, prioritization, resourcing and budgetingContribute to Investigator’s Brochure writing for IND/CTA and FIH protocolsSupport fund-raising and out-licensing; regular BD interactions with pharma and VCsJSC member in a multi-year collaboration with a top pharma on novel AD targets (neuroinflammation focus)• Define strategic goals to meet milestones on time• Plan and budget internal/external resources• Review legal documentation (CDA, MTA, alliance contracts)Liaise with CROs for pre-clinical/clinical studies• Identify CROs and relevant in-vitro/in-vivo models for MoA validation• Use DMPK data to design dose regimens for in-vivo PoCEngage with external Scientific Advisors and SABsEstablish strategic collaborations with leading KOLs• Define achievable goals ensuring partner engagement• Oversee data generation for internal (BD/IND) and external outputs (publications)Enhance company profile through international presentations and peer-reviewed publicationsIdentify, assess and implement new technologies (e.g, advanced instruments, hIPSC methods) and processes (e.g, electronic lab notebooks) to increase capability and efficiency.
EDUCATION
EF Educational Tours
Summer English course in Brighton, UK
Universita' Degli Studi Del Piemonte Orientale 'Amedeo Avogadro'
B. Sc., Biology and Pharmaceutical technology
University of Helsinki
Doctor of Philosophy (PhD), Neuropharmacology
Mc Callan English School (Oxford St, London)
English
EF Educational Tours
Summer English course in Brighton, UK
Sutherland School, Novara, Italy
English
Universita' Degli Studi Del Piemonte Orientale 'Amedeo Avogadro'
M. Sc. (Pharm), Pharmacology
SKILLS
ABOUT BERNARDINO OSSOLA
An experienced in-vitro and in-vivo pharmacologist with a PhD in Neuropharmacology and over 19 years of drug discovery experience in academia and biotech industry in Neuroscience, Immune-Oncology, and autoimmune disease. Experienced leader and manager of integrated multidisciplinary drug discovery programs from target assessment / selection to early clinical development. Management of company therapeutic area strategy and devising disease area from internal and external networks.
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