Zofia Komsta
Vice President, Research and Development @Cristae Therapeutics
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WORK HISTORY
Vice President, Research and Development @Cristae Therapeutics
Cristae Therapeutics is a biotech company developing small-molecule therapies designed to restore mitochondrial function across multiple severe disorders. These range from neurodegenerative diseases like Parkinson’s disease, Alzheimer’s disease and ALS to rare conditions affecting the brain, heart and peripheral tissues.Built on more than a decade of scientific research, Cristae\'s core strength lies in its proprietary library of more than 700 compounds designed to improve mitochondrial function.
EDUCATION
University of Leeds
PhD, Organic Chemistry
Warsaw University of Technology
MSc, Chemistry, Chemical Technology
The Institute of Organic Chemistry, Polish Academy of Sciences
MSc, Organic Chemistry
Harvard Business School
Advent Leadership Academy - Executive Education
Henley Business School
Executive MBA
SKILLS
ABOUT ZOFIA KOMSTA
With a solid track record in leading projects within the pharmaceutical industry, I specialise in planning, managing, and executing complex synthetic routes for APIs and their intermediates. My expertise spans from milligram to kilogram-scale synthesis and process development, culminating in successful technology transfer and pilot production.As a skilled leader, I manage multiple projects concurrently, maintaining clear communication and fostering a culture of innovation and psychological safety that encourages team creativity and accountability. My experience in multinational team leadership has enhanced my ability to empower and motivate, driving teams to deliver exceptional results.Technically adept in API synthesis and precursor development, my background is grounded in process chemistry, development, and optimisation, ensuring compliance with cGMP standards. I work effectively with international CMOs and CROs, creating cost models and simulations for production cost estimations, and have a practical understanding of the engineering aspects related to chemical manufacturing. My approach is proactive and versatile, endorsing new technologies and innovative thinking for continuous improvement.
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