Zhenyu Gu

Executive Director CMC | Analytical Sciences | Process Development | Formulation Development | Tech Transfer | DS/DP manufacturing | CDMO/CRO management | Regulatory Submissions | Protein, CGT, ADC/AOC, mRNA

Role
Executive Director, Cmc, Analytical Sciences at Xencor
Location
South San Francisco, CA, US
LinkedIn followers
500 followers

About Zhenyu Gu

About 20 years of biotech leadership accelerating therapeutics across diverse modalities, from preclinical through IND/BLA to commercialization. Expertise spans assay development, formulation, drug substance/drug product manufacturing, characterization, validation, tech transfer, molecule design/developability, device integration, and regulatory filings in complex, fast-paced environments.Extensive experience managing global CDMO/CRO partnerships, leading high-performing cross-functional teams, and resolving critical CMC challenges across analytical, formulation, and manufacturing domains.Focused on shaping CMC strategies that advance pipeline assets while enabling long-term scalability and regulatory success. Major contributions to multiple IND, IMPD and BLA/NDA submissions—supporting both early-stage and commercial products through strategic oversight, scientific leadership, and cross-functional collaboration.

Experience

  1. Executive Director, Cmc, Analytical Sciences

    Xencor

    Dec 2025 — Present

Education

  • Chinese Academy of Sciences

    Doctor of Philosophy - PhD, Biochemcial Engineering

  • Uppsala University

    Visiting PhD researcher, Biochemcial Engineering

Skills

  • Protein Engineering
  • Elisa
  • Hplc
  • Assay Development
  • Western Blotting
  • Purification
  • Protein Chemistry
  • Characterization
  • Chromatography
  • Sds-Page
  • Protein Purification
  • Cell Culture
  • Mass Spectrometry
  • Biochemistry
  • Biophysics

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