Zeinab Fereshteh

About Zeinab Fereshteh

As a Senior Scientist at NJ Bio, Inc, I bring over three years of expertise in antibody-drug conjugates (ADCs), bioconjugation, and drug development. My work focuses on developing cutting-edge ADC solutions, from strategic design to scalable implementation, with a strong emphasis on high-throughput workflows and controlled Drug-to-Antibody Ratios (DAR). Skilled in bioconjugation, I specialize in cleavable and non-cleavable linkers, site-specific enzymatic conjugation, and troubleshooting complex conjugation systems. My professional journey, supported by a PhD in Materials Engineering, reflects a commitment to advancing therapeutic innovation through scientific precision and collaboration. By leveraging my skills in Good Manufacturing Practice (GMP), project management, and drug development, I contribute to delivering innovative solutions that address complex challenges in modern biopharmaceuticals.

Experience

1. Senior Scientist

   NJ Bio, Inc.

   Dec 2022 — Present · NJ, US

   Led a cross-functional team in delivering cutting-edge bioconjugation and ADC solutions, taking full scientific ownership from strategy to scalable implementation.* Oversaw the design, optimization, and development of innovative ADC candidates, including cleavable and non-cleavable linkers (Val-Cit, SPDB, CL2A, MC, SMCC) and site-specific conjugation approaches (transglutaminase-mediated), ensuring controlled DAR and reproducible stability.* Developed and executed high-throughput ADC conjugation workflows, enabling rapid screening of linker-payload combinations across multiple antibody platforms.* Troubleshot and optimized conjugation conditions across diverse payloads and antibodies, delivering consistent, high-quality bioconjugates.* Skilled in utilizing a wide range of analytical instruments, including HPLC, UPLC, RP-MS, SEC, UV-Vis.* Worked closely with cross-functional teams to tackle complex ADC challenges and translate scientific insight into actionable solutions.* Committed to upholding the highest standards of quality and safety in pharmaceutical research and development.

Education

• University of Kashan

  Bachelor's degree, Applied Chemistry

  2003 — 2007

• Isfahan University of Technology

  Doctor of Philosophy - PhD, Ph.D. Bio Medical Engineering

  2009 — 2014

• University of Kashan

  Master's degree, Chemistry (Nano Science and Nano Technology)-Institute of Nano Science and Nano Technology

  2007 — 2009