Yongbo Yuan
Lead Scientist @IFF
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WORK HISTORY
Lead Scientist @IFF
Wilmington, DE, US
EDUCATION
Northeastern University (CN)
Bachelor's degree
Universität des Saarlandes
Doctor of Philosophy (Ph.D.), Biochemical Engineering
University of Science and Technology Beijing
Master's degree, Biochemical Engineering
SKILLS
ABOUT YONGBO YUAN
Synthetic biology & High throughput robotic screening & Upstream bioprocess development focusing on developing/optimizing industrial microbial strains for enzymes,flavor ingredients, chemicals, recombinant proteins production. Experienced in scale up of industrial fermentations from microtiter plate scale to pilot-scale.2. Developed DNA assembly protocol for high throughput robotic automation system.3. Applying metabolic engineering/directed evolutionary strategy in E. coli to increase solvents tolerance as well as in industrial Saccharomyces cerevisiae and anaerobic bacterium to improve biofuels, enzymes production.4. Developed innovative methods for metabolic network activity characterization using mass spectrometry. GCMS for metabolic flux analysis and MALDI-TOF-MS for metabolites quantification.5. Highly experienced in High throughput robotic screening, bench top bioreactor fermentation process optimization, DNA assembly, directed evolution, multi-enzyme pathway optimization, enzyme characterization/enzymatic kinetic study, protein expression/purification, library construction/screening, metabolic flux analysis, isotope labeling experiment design/data analysis heterologous genes successive integration, PCR, gene expression, ncRNA & protein interaction, Northern Blot. Skilled in analysis techniques such as HPLC, LC-MS, GCMS, GC-C-irMS, MALDI-TOF MS, Flow cytometry.7. Experienced in scientific paper, report writing and proficient with JMP11, Vector NTI, MatLab, RNAfold, BLAST and OriginLab computer software. Previous working experiences provide me market and economic perspective as well as excellent leadership and communication ability
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