Yiran Wang

Experience

1. Principal Scientist

   Bristol Myers Squibb

   Dec 2019 — Present · MA, US

   o Drove the design and execution of experiments for the development of cGMP manufacturing processes and associated process controls, supporting clinical and commercial supply readiness for diverse modalities, including monoclonal antibodies (mAbs), bispecific mAbs, ADC intermediates, microbial-derived proteins, and plasmidso Facilitated and supervised technology transfer and process implementation at GLP (500L) and GMP manufacturing facilities, both internally and with external partnerso Designed, executed, and analyzed process characterization (PC) studies to define critical process parameters (CPPs) and critical quality attributes (CQAs), utilizing statistical design of experiments (DOE) to evaluate process robustness and establish control strategieso Authored relevant CMC sections for regulatory submissions and supported responses to regulatory agencieso Represented process development in CMC subteams and collaborated closely with internal stakeholders, including Analytical Development, Quality Control, Research, Quality Assurance, Regulatory, and Project Management, to troubleshoot issues and develop robust drug substance processes

Education

• Tianjin University

  Bachelor of Science - BS

• University of Virginia

  Doctor of Philosophy - PhD