Ying Shen
Director at Takeda Pharmaceutical Company
- Role
- Director, Lead Tech Development for Cell and Protein Therapy at Takeda
- Location
- Cambridge, MA, US
- LinkedIn followers
- 500 followers
About Ying Shen
Over 20 years experience that includes molecular and cell biology, antibody production cell line development, next-generation (NextGen) sequencing, CHO genome engineering, protein expression and purification, high-throughput drug screening and assay development• Skilled in experimental design, data interpretation, reports assembly, data and protocol management • Excellent manager and team player with strong communication and interpersonal skills• Established ability of meeting deadlines, multi-tasking, project and people management
Experience
Director, Lead Tech Development for Cell and Protein Therapy
Jan 2023 — Present · Cambridge, MA, US
Lead a team to engineer and improve Chinese Hamster Ovary (CHO) hosts to achieve higher protein titers with desired modification/quality• Lead a team to improve screening method to identify high titer clones• Lead a team to make stable HEK293 cell lines expressing retroviral vector with high titer (>1E7 TU/mL)• Lead a team to use NGS to facilitate CHO or HEK293 clone screening to support therapeutic protein or cell therapy pipelines • Lead a team to develop new NGS tools like genotyping or adventitious pathogen detection
Education
Nankai University
Bachelor's, Biochemistry
The University of Tennessee Health Science Center
Ph.D., Molecular and Cell Biology
Skills
- In Vitro
- Drug Discovery
- Biotechnology
- Protein Purification
- Biochemistry
- Flow Cytometry
- Assay Development
- Life Sciences
- Tissue Culture
- Elisa
- Molecular Biology
- Chromatography
- Cell Biology
- Molecular Cloning
- Immunofluorescence
- Cell Culture
- Bioinformatics
- High Throughput Screening
- Western Blotting
- Genetics
- Immunoprecipitation
- Cell
- Dna
- Pcr
- Protein Expression
- Protein Chemistry
- Immunohistochemistry
- Qpcr
- Rt-Pcr
- Genomics
- Transfection
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