Ya-Ting Chang
Scientist @ Denali Therapeutics | PhD in Molecular Genetics & Biochemistry
- Role
- Scientist at Denali Therapeutics
- Location
- Alameda, CA, US
- LinkedIn followers
- 500 followers
About Ya-Ting Chang
Professionally, I am a medical technician, yeast geneticist, and molecular biologist by training. The past projects I have involved in include Hepatitis C virus (HCV)-induced carcinogenesis and the role of telomere maintenance in aging. From a disease prevention point of view, my research of HCV pathogenesis in human-provided a new insight into how HCV viral protein hijacks the cellular pathway Wnt/beta-catenin signaling to promote cancer development. The major contribution of my Ph.D. research is to elucidate how telomere structure is maintained during the DNA replication process. Loss of telomere DNA leads to cell death and aging. Telomere-bound proteins exert the major protection and function of the telomere. Understanding the detailed mechanism of telomere maintenance helps to develop not only the therapeutic strategies of preventing the early aging process in adults and treating aging-related genetic diseases but also the better treatment with telomerase positive cancer cells. With all my training in basic research for finding the fundamental principles of life, I believe that translating the knowledge to the clinical application on human and public health is an essential task. My goal will be pursing clinical treatment using research knowledge from basic science. Precision medicine will be the future of healthcare. Using the most pioneering genome information to diagnose the diseases will provide the best treatment for the patients.Personally, I am a passionate researcher who asks questions, search for answers tirelessly, and is completely driven by curiosity. There is nothing but multiple disciplinary environments more attractive to me when my eagerness for answers is accelerating. Collaboration with different experts and exchange of ideas are the most enjoyable interaction in the scientific research process. Learning science and doing research is my life as a whole. Science, my true love, so to speak.
Experience
Scientist
Oct 2024 — Present
Education
University of Illinois Chicago
PhD, Biochemistry
2006 — 2013
National Yang Ming University
Master's Degree, Biochemistry
2001 — 2003
National Taiwan University
Bachelor's Degree, Medical Technician
1995 — 1999
Skills
- Protein Chemistry
- Molecular Biology
- Fluorescence Microscopy
- Cell Biology
- Protein Expression
- Protein Purification
- Elisa
- Chromatin Immunoprecipitation
- Cell
- Pcr
- Co-Immunoprecipitation
- Yeast Two-Hybrid
- Real-Time Polymerase Chain Reaction (Qpcr)
- Western Blotting
- Research
- Cell Culture
- Southern Blot
- Genetics
- Immunoprecipitation
- Molecular Cloning
- Biochemistry
- Immunohistochemistry
- Qpcr
- Microscopy
Find verified contacts for anyone on LinkedIn
Unifers gives sales teams verified emails and direct dials, enriched profiles, and outreach that lands in the inbox.
Free plan included · No credit card required
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.