Xufeng Cao
Scientist III, Medicinal Chemistry at Olema Oncology
- Role
- Scientist Iii, Medicinal Chemistry at Olema Oncology
- Location
- San Francisco, CA, US
- LinkedIn followers
- 500 followers
About Xufeng Cao
A 10+ years experience medicinal chemist focusing on the discovery and development of…
Experience
Scientist Iii, Medicinal Chemistry
Jun 2021 — Present · San Francisco, CA, US
Discover novel and potent Complete Estrogen Receptor Antagonist (CERAN), inhibitors of PI3Kα and CDK2 that conform to anti-breast cancer Target Candidate Profile.2. Performing lead optimization through the design and synthesis of proprietary small novel anti-breast cancer molecules with improved properties. Elucidating instructive SAR by interpreting complex data sets derived from biological and physicochemical assays. Engaging in the scale-up of selected target molecules and high-value intermediates. Providing clear presentations of research progress to the chemistry group, cross-functional project teams, and executive leadership.6. Directly managing internal associate scientists and engaging in the management of CRO Chemistry. Generate for synthetic targets, communicate the ideas. Identify synthetic problems and propose the solution. Track the progress of project and make sure the timeline is met.7. Supporting the drafting of patent applications, scientific publications, and external presentations.
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