Xinbing Han

WORK HISTORY

EDUCATION

SKILLS

ABOUT XINBING HAN

Drug Discovery & Preclinical Development: 10+ years of experience in drug discovery and preclinical development in the Pharma industry. Strong drug discovery and preclinical expertise in areas of autoimmune diseases, fibrosis, cardiovascular and metabolic diseases. Experience in identifying several targets in discovery, validating and advancing molecules to the clinic. Experience reviewing regulatory study reports & pharmacology protocols for small molecule programs. Published 33 articles in peer-reviewed journals and 2 book chapters. Matrix Team Experience: Closely worked with a team of 15+ scientists across four divisions. Strategized to achieve program milestones with teamwork skills. Research skills: Cytokines/chemokines, GPCRs, growth factors, receptors, kinases, enzymes, and transporters. Developed protein-protein interactions, biochemistry, in vitro & ex-vivo assays, translational research, and biomarkers. Strong experience in immunology, pharmacology, biochemistry, molecular and cell biology. Established preclinical cell and animal models in areas of autoimmune diseases/inflammation, cardiovascular and metabolic diseases. Worked on differentiated modalities including large and small molecules, cyclic peptides, chemically modified RNA, DNA plasmids, HSC and hiPSC, siRNA, shRNA, viral and non-viral delivery, cell and gene therapies.Collaboration: Successful collaborations with cross functional teams lead to the portfolio entry of the discovery program. Partnered with internal and external stakeholders, KOLs, academic institutions, and CROs, leading to the achievement of key deliverables.