Wenchao Sun
Principal Scientist at Amgen
- Role
- Principal Scientist at Amgen
- Location
- Thousand Oaks, CA, US
- LinkedIn followers
- 500 followers
About Wenchao Sun
Highly motivated and detail-oriented scientist with extensive expertise in protein purification and characterization, bispecific Ab discovery and development, preclinical drug development, LCMS analysis of small molecules and drug delivery.• Experience with IND application and CMC development.• Proven track record with 14 peer reviewed papers, 2 book chapters, and 2 conference oral presentations.• Strong management, communication, and independent problem solving skills, project leadership.Specialties:Mammalian protein expression (ExpiCHO), protein production (GE WAVE bioreactor) and protein purification (AKTA chromatography: affinity, IEX, SEC, HIC, mixed mode)Protein characterization (Analytical SEC, Tm Tagg, Kinetics and Epitope Binning using Octet, LabChip, Serum Stability using labeled proteins)LC-MS/MS (QTRAP PK, biodistribution, metabolite ID) and RP-HPLCTransdermal protein and drug delivery Non-viral gene delivery using polymer nanoparticles
Experience
Principal Scientist
Jul 2023 — Present · Thousand Oaks, CA, US
Antibody purification and analytics. Multi-specific antibody discovery and development. Early stage high-throughput developability assessment.
Education
Tsinghua University
B.Sc., Biological Science and Biotechnology
2001 — 2005
Case Western Reserve University School of Medicine
Ph.D., Biochemistry
2005 — 2011
Skills
- Cell Biology
- Protein Purification
- Tem
- Protein Chemistry
- Molecular Cloning
- Biochemistry
- Lc-Ms
- Bioconjugate Chemistry
- Click Chemistry
- Flow Cytometry
- Hplc
- Cryosectioning
- Genotyping
- Thiol/Disulfide Chemistry
- Dna Nanoparticle
- Liquid Chromatography-Mass Spectrometry (Lc-Ms)
- Western Blotting
- Microneedle Technology
- Molecular Imaging
- Non-Viral Gene Delivery
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