Vishal Verma

Senior Principal Scientist @Genentech

South San Francisco, CA, US

Broad experience leading teams in a wide variety of disease areas in drug discovery, including oncology, immunology and infectious disease. Have worked on multiple novel modalities such as both reversible and irreversible covalent MOAs, antibody-drug conjugates and degraders and molecular glues. Experienced with membrane and cytosolic small molecule targets utilizing both active site and allosteric mechanisms of inhibition. Harnessed both cryo-EM and crystal structure based drug design to advance programs as well as ligand and pharmacophore based design.As a team lead, coordinated amongst a wide variety of multi-disciplinary groups including computational chemistry, structural biology, biochemical pharmacology, in vitro biology, in vivo biology, DMPK, safety, pharmaceutics, etc. to advance projects. Engaged with external partners including managing large teams of CRO chemists. Contributed to teams delivering multiple candidates into development and the clinic. Gaining experience in following programs into development. Contributing to business development due diligence evaluations for critical targets to bring into the portfolio.

Northwestern University

BA, Chemistry & Integrated Science

Stanford University

Ph.D., Organic Chemistry - Professor Paul A. Wender