Ving Lee
Chief Scientific Officer/Chem Syntheses Optimization/Drug Discovery-Development/Anti-infectives/Oncology - building biotechs and contract research organizations (CROs) from ground up towards IPOs or acquisitions
- Role
- Chief Scientific Officer at Adesis, Inc.
- Location
- San Francisco, CA, US
- LinkedIn followers
- 500 followers
About Ving Lee
As chief scientific officer at Adesis, I provide scientific and discovery guidance on the company’s chemistry operations. Also advise clients on their project’s medical chemistry and biology. Clients come to Adesis when they have complex chemistry problems that require creativity of thought. When our world-class team of chemists works on a project, they don’t just manage it – they eat, sleep and think about the project. The ultimate goal is the client\'s success, by attaining compounds in producible format. That includes rapid turnaround response, exemplary scientific acumen and minimal logistical issues, all within budget.Over the past 15+ years, I have extensive experience in developing high-performing research organizations, fostering business expansion by continuous improvement in R&D processes, by promoting cross-functional collaboration between scientific, non-clinical, and manufacturing staff, and leading organizational restructuring/turnaround initiatives.Evocative Career: Built four biotech start-ups, driving innovation and scholarship in anti-infectives and other therapeutics throughout career (with 70+ patents, 70+ peer-reviewed publications, and membership of NIH study sections). Spearheaded the growth of Adesis from a small medicinal chemistry and process chemistry contract research organization (CRO) into an organization of 100+ employees with pre-GMP support capabilities. Established and grew Limerick BioPharma into a biotech venture by leveraging pharmacological insights of first-in-class semi-synthetic natural product lead molecules, securing $45M in series A-C funding. Managed and optimized scientific discovery programs for new boron-based therapeutics at Anacor Pharmaceuticals as its first employee, leading to rapid growth and $22.6M in non-dilutive funding from DARPA.I have significant expertise in antibacterial, anticancer and immunosuppressive agents, as well as extensive experience in transport technology in eukaryotes and prokaryotes, and natural products.Scientific accomplishments include:• … beta-lactams for problematic gram-positive pathogens, tetracyclines for problematic pathogens, uridyl-peptide antibiotics for problematic gram-negative pathogens, non-classical antibiotics, inhibitors of bacterial and mammalian efflux pumps, and natural products. • … discovery of new anti-infectives, including the glycylcyclines, carbapenems, enhanced third-generation cephalosporins, benzoxaboroles, beta-lactamase inhibitors, macrolides, new oncology agents, and metabolic modifiers
Experience
Chief Scientific Officer
Jan 2005 — Present
Adesis, Inc, is a premier chemistry solution company. As a chemistry CRO, the company partners with biotech, pharma and specialty chemical industry clients to accelerate client research and manufacturing goals. Adesis specializes in organic and organometallic synthesis – in milligrams to multikilogram quantities – and provides expertise in custom synthesis chemical manufacturing, research and development. “Partner with us and Adesis becomes a trusted extension of your R&D team.”
Education
University of Illinois Urbana-Champaign
Master of Science - MS, Organic Chemistry and Toxicology
The Ohio State University
Bachelor of Arts - BA, Chemistry
Harvard University
NIH Post-grad, Organic Chemistry
University of Illinois Urbana-Champaign
Ph.D., Organic Chemistry
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