Vijetha Balakundi
Data analyst @ Mass General Brigham | Broad Institute of MIT and Harvard | Bioinformatician | Machine Learning Enthusiast
- Role
- Research Data Analyst Ii at Mass General Brigham
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
Experience
Research Data Analyst Ii
Mar 2024 — Present · Belmont, MA, US
GREx (Gene Regulation Expression): Developed and applied elastic net models to integrate RNA-seq gene count data and Proteomics with genotype data, identifying key genetic variants influencing gene expression in the context of Post-Traumatic Stress Disorder (PTSD).• Genotype Data Pipeline Development: Built an end-to-end pipeline for genotype data processing, including idat to vcf conversion, quality control (QC), and imputation, using bioinformatics tools and workflows.• Polygenic Risk Score (PRS) Calculations: Leveraged Genomes and UK Biobank as reference panels, combined with European and African Genome-Wide Association Studies (GWAS), to enhance PRS calculations for PTSD and MDD research.• Unsupervised Machine Learning: Designed and implemented unsupervised learning algorithms, including principal component analysis (PCA) and clustering, to analyze pre- and post-treatment survey data, evaluating treatment-related changes.• Workflow Optimization: Improved model performance and ensured reproducibility by implementing Docker-based workflows for the Wellcome Leap MCPsych Project.
Education
Boston University
Masters
2022 — 2023
PES University
Bachelor of Technology - BTech
2018 — 2022
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