Verenice Paredes
Senior Scientist Antibody Discovery-engineering @Synthekine
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WORK HISTORY
Senior Scientist Antibody Discovery-engineering @Synthekine
Menlo Park, CA, US
Constructed and screened VHH phage display libraries to generate hits for therapeutics programs.Selected accomplishments:• Established VHH Phage Display antibody discovery platform, allowing generation of multiple antibody panels for different research programs and resulting in patent authorship.• Supported surrogate cytokine agonist development programs, including collaborative program with Sanofi, by selecting high-affinity VHH antibodies through phage display campaigns.• Aided in vivo antibody discovery projects by monitoring antibody titers in in-house immunized mice and antigen-specific single B-cell isolation and sequencing via FACS followed by RT-PCR or single-cell 10x genomics.
EDUCATION
Universidad de Guadalajara
Bachelor of Science (BS), Pharmacobiology Chemistry
Kyung Hee University
Doctor of Philosophy - PhD, Biotechnology
ABOUT VERENICE PAREDES
Results-driven and analytical professional with robust foundation in antibody discovery, protein engineering, molecular biology and protein production, leading therapeutic candidate generation. Strategic problem-solver who effectively collaborates across cross-functional teams, driving impactful research that translates into therapeutic breakthroughs. Committed to scientific excellence and continuous innovation, passionate about developing novel biologics that address unmet medical needs and improve patient outcomes. Key contributor to patents and peer-reviewed publications. Project Leadership | Analytical Thinking | Troubleshooting | Teamwork | Multi-Tasking | Adaptability | Fast Learning Technical Skills Antibody Discovery/Protein Engineering: Phage Display, Single B-Cell Screening and Sequencing using FACS/MACS or 10x Genomics; Sanger and NGS Antibody Sequence Analysis for Hit Identification Protein Expression: Mammalian Transient/Stable Transfection, Bacterial Induction Protein Purification: FPLC (IEC, SEC, HIC, RPC, IMAC, Affinity, Protein A/G), Ultrafiltration, AKTA Systems Analytical: SDS-PAGE, Western Blotting, ELISA, Flow Cytometry, Immunofluorescence Molecular Biology: Expression Construct Design, PCR, RT-PCR, Restriction and Golden Gate Cloning, Gibson Assembly, Site-Directed Mutagenesis, NGS Library Construction Data Analysis / Management: Sequencher, Clustal, Abalign, Excel, FlowJow, GraphPad, Benchling
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