Vasudev Kantae

WORK HISTORY

EDUCATION

ABOUT VASUDEV KANTAE

Experienced bio-analytical scientist with expertise in application of mass spectrometry (12+yrs) in early drug discovery capable of driving business-directed decisions supporting discovery of life-changing Oncology therapeutics. Leading the departmental mass spectrometry based quantitative (bio)analysis thrust to develop novel cellular and biochemical workflows underpinning Structure-Activity-Relationship (SAR) and mechanism of action (MoA) studies to support hit-to-lead drug discovery programs.Working synergistically across cross-functional teams to foster label-free technologies to deliver efficacy and safety data in early drug discovery. •Experienced project manager in delivering tailored mass spectrometry strategy across drug discovery programmes•Passion for innovation with the ability to question the status quo to provide innovative solutions and processesValued leader of key stakeholders across cross-functional teams in planning, execution and timely delivery of the data throughout the discovery pipeline from target identification to candidate selection. Leading the implementation of high-throughput mass spectrometry workflows to deliver mechanistic packages to influence project decisions. Synergistically collaborated across the fields of analytical biochemistry, enzymology, drug pharmacology (PK/PD) and biology for innovative drug and molecular mechanistic insight supporting drug discovery. Global department mass spectrometry (MS) lead, matrix management of various MS teams in Sweden and US to delivery MS-based mechanistic strategy to projects. Managed an internal budget in implementation of automation to support high-throughput mass spectrometry workflowsDepartment employee representative to create AstraZeneca as a great place to work.Promoting scientific research through 17-external peer-reviewed publications, oral talks, course tutor and chairing meetings/sessions at various internal and external conferences and initiating external collaborations. My expertise in following areasBioanalysis (mass spectrometry)In-Vitro and ex-vivo pharmacologyProteomics and metabolomics with drug pharmacology (PK-PD)- Systems Pharmacology Bioanalysis: Proteins, Oligos, Small molecules (metabolites and lipids) and drugs with various LC-MS technologiesEnzymology in early drug discovery Covalent based drug discovery (Target selection, screening, hit-to-lead) Oncology, inflammation and metabolic disease are area of expertise Other competencies: Project management, communication, strategic vision, collaboration, systemization, decisiveness