Urs Mueller

Senior Director | Site Head IT OT @ Genentech | Driving Digital Transformation

Role
Senior Director IT Ot at Genentech
Location
Hillsboro, OR, US
LinkedIn followers
500 followers

About Urs Mueller

I’m a global engineering and operations leader with extensive experience delivering large-scale CAPEX programs, greenfield facilities, and technology transformations across the biotech, pharmaceutical, and life sciences industries.Throughout my career, I’ve led complex, multinational projects—building new manufacturing sites in China, modernizing infrastructure across Asia-Pacific, and guiding high-value investments in the U.S. My focus has always been clear: connect engineering excellence with operational readiness to enable sustainable growth in highly regulated environments.My expertise covers capital project delivery, automation, process engineering, and IT OT integration, bridging the gap between corporate strategy, GMP compliance, and plant-floor execution. I’ve built and led cross-functional global teams, ensuring that technology, process, and people align to deliver measurable outcomes—on time, on budget, and in full compliance.Known for leading through clarity, trust, and a bias for action, I bring a disciplined yet collaborative approach to global program leadership. Titles matter less than impact—I measure success by what gets built, scaled, or quietly prevented.If your organization is investing in new manufacturing capacity, facility expansion, or large-scale engineering transformation, I’m open to connecting on how strong, integrated engineering leadership can turn complex programs into lasting operational v••••••••@swissmarket.com

Experience

  1. Senior Director IT Ot

    Genentech

    May 2022 — Present · Hillsboro, OR, US

    Hired to build a fully integrated IT/OT organization from scratch, Urs took on a complex leadership challenge in one of Genentech’s most regulated environments. Site teams were skeptical, automation groups resisted the shift, and global tools didn’t align with local realities.He stood up a 40-person team, secured buy-in across departments, and bridged the cultural divide between global IT and on-the-ground operations. Alongside this, he helped lead two massive transformations—a new SAP rollout and MES system upgrade—both critical to Genentech’s shift into digital manufacturing.​When systems clashed and production was on the line, Urs became the voice of execution, ensuring continuity without compromise. The IT/OT function he built is now embedded in site leadership and supports advanced therapies at scale.

Skills

  • Business Intelligence
  • IT Outsourcing
  • Sharepoint
  • Computer System Validation
  • International Project Management
  • Infrastructure
  • Gxp
  • Information Technology
  • Process Improvement
  • IT Service Management
  • Change Management
  • Intercultural Communication
  • Asia Pacific
  • Leading Large Teams
  • Line Management
  • Data Center
  • Vendor Management
  • Erp
  • Program Management
  • IT Operations
  • Itil
  • Hardware Diagnostics
  • Cross-Functional Team Leadership
  • Disaster Recovery
  • Active Directory
  • Service Delivery
  • Integration
  • Project Portfolio Management
  • Technical Support
  • Business Analysis
  • Prince2
  • Customer Service
  • Governance
  • Service Management
  • Enterprise Architecture
  • Service Desk
  • IT Management
  • Incident Management
  • Solution Architecture
  • Pmo

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Urs Mueller — Senior Director IT Ot at Genentech in Hillsboro, OR, US | Unifers