Tv Radha Krishna Mullapudi
Managing Director @Pharmajen Laboratories
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WORK HISTORY
Managing Director @Pharmajen Laboratories
Hyderabad, IN
EDUCATION
Henry Harvin Education
Certified Business Analytics Practitioner (CBAP), Business Statistics
Birla Institute of Technology and Science, Pilani
Doctorate, Pharmaceutical Sciences
Rajiv Gandhi University of Health Sciences
Master of Pharmacy, Pharmacology
Rajiv Gandhi University of Health Sciences
Bachelor of Pharmacy - BPharm
Certara University
Introduction to Phoenix WinNonlin plus the IVIVC Toolkit , Pharmaceutical Sciences
SKILLS
ABOUT TV RADHA KRISHNA MULLAPUDI
As a Scientist with over 15 years of expertise in ADME and DMPK, I lead preclinical research that accelerates drug development for pharmaceutical partners worldwide. At PharmaJen laboratories \"a leading CRO\", I specialize in designing and executing high-impact studies that optimize drug candidates, ensuring robust data for regulatory submissions and clinical success.My Core Expertise Includes:Preclinical Formulation: Developing formulations to enhance bioavailability and stability for early-stage compounds.In-Vitro & In-Vivo DMPK: Conducting metabolic stability, metabolite identification, and pharmacokinetic studies across species (mice, rats, dogs, monkeys) using advanced LC-MS/MS and UFLC-MS/MS platforms.Drug-Drug Interactions: Assessing CYP inhibition/induction, UGT screening, and non-CYP metabolism to ensure safety and efficacy.Quantitative Bioanalysis: Leveraging Certara’s Phoenix Win-Nonlin for precise non-compartmental analysis and bioanalytical insights.High-Throughput Screening (HTS-ADME): Streamlining metabolic stability, CYP interactions, and permeability (Caco-2/MDCK) for faster decision-making.Physicochemical & Binding Studies: Measuring lipophilicity, solubility, plasma protein binding, and tissue/microsome binding to inform drug design.I’m passionate about bridging science and strategy to deliver actionable insights for clients, from startups to global pharma. My work has supported of NCE\'s \"optimized ADME profiles for novel compounds\". Certified as a Non-Compartmental Analysis Analyst by Certara, I combine technical rigor with a client-focused approach to drive project success.Let’s connect to discuss how I can support your drug development pipeline with tailored ADME/DMPK solutions. Reach out at h••••@pharmajen.com or via LinkedIn to explore collaboration opportunities
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