Tsunghan Hsieh

Postdoctoral Associate @Sanford Burnham Prebys

San Diego, CA, US

Specializing in T cell biology, integrating both experimental and computational approaches- Investigating epigenetic rejuvenation strategies to restore aged immune cell function by reprogramming their epigenetic landscapes, with a focus on improving CAR T cell efficacy- Conducting multi-omics analyses (RNA-seq, ATAC-seq, methylation sequencing) to compare aged vs. young immune cells and assess the impact of reprogramming on CAR T cell function- Utilizing a melanoma mouse model to evaluate the therapeutic potential of rejuvenated T cells in cancer immunotherapy- Developing R packages and interactive web applications to analyze and visualize bioinformatics data, streamlining multi-omics research workflows- Bridging bioinformatics and wet-lab research to enhance immune cell persistence, cytotoxicity, and overall therapeutic potential in adoptive cell therapy.

Okinawa Institute of Science and Technology

Doctor of Philosophy - PhD

National Yang Ming University

Bachelor's degree

National Yang Ming University

Master's degree