Theodore Sana

Metabolomics and lipidomics leader in disease agnostic research for both early discovery and clinical biomarker ID, target ID, and pipeline impact

Role
Director, Metabolomics at Merck
Location
Cambridge, MA, US
LinkedIn followers
500 followers

About Theodore Sana

Senior applied research scientist and manager, with broad bio-analytical and data analysis expertise * Metabolomics lead, early drug discovery in large Pharmaceutical firm * Member of the Mass Spectrometry & Biophysics Leadership Team: involved in building strategy, and developing careers for my reports * Expertise in clinical, pre-clinical and basic research exploratory experiment design, analysis and interpretation of results * Actively developed talent, including scientists, coops and interns, maximizing diversity of thought and inclusion that empowers and and engages all team members * Proactively engaged stakeholders across global org in both functional and therapeutic areas to define strategies for metabolite/lipid biomarker ID (prognostic/diagnostic) and target ID * Maintained a strong partnership with biostatistics, bioinformatics and systems biology teams to help build IT supported data analysis pipeline * Balanced strategic investment in new technologies and tactical utilization of solutions across global organization to drive scientific impact * Evaluated new HW & SW technologies, CROs for externalization of additional Metabolomics & lipidomics analyses * At Agilent: Marketing & business development management experience for Life Sciences; assessed new opportunities to help drive incremental business in adjacent and new markets * Built several strong, collaborative relationships with KOLs in academia, and served as technical contributor on research grants * Worked cross-functionally across the global organization to help advance company strategic initiatives * Experienced mentoring, training and managing technical personnel * Prolific writer of technical documents: peer-reviewed publications, internal applications notes, presentations, webinars Core competencies: Technical expertise in untargeted and targeted metabolomics, data analysis and visualization of small molecule metabolites, proteins and transcripts using proprietary and open source software. Mass Spectrometry: LC/MS, LC/MS/MS, and GC/MS for both small and large molecules. Genomics, proteomics, protein biophysical characterization, SPR and cell-based binding assays, bioassays, receptor, assay automation, FACS, PCR, molecular and cellular biology, computational biology, biochemistry, biomarker discovery, DOE, familiar with R-scripts. Extensive experience establishing academic collaborations and performing technical due diligence

Experience

  1. Director, Metabolomics

    Merck

    Jun 2017 — Present · Cambridge, MA

    Established a new metabolomics laboratory and capabilities for doing Molecular and Cellular Metabolism at Merck & Co. Led a team of accomplished scientists performing disease agnostic research including: immuno-oncology; neurodegenerative diseases; metabolic diseases such as T2D, NAFLD, NASH; vaccine hypo-responses

Education

  • Dartmouth Medical School

    PhD, Molecular Pharmacology

  • Cambridge Tutors, London, U.K.

    GCE O and A levels high school diploma

  • Philadelphia College of Pharmacy & science

    B.S., Toxicology

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Theodore Sana — Director, Metabolomics at Merck in Cambridge, MA, US | Unifers