Timothy Cooper
Bioprocessing/ Analytical Chemistry
- Role
- Analytical Chemistry Ext Scientist at Novartis
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
Experience
Analytical Chemistry Ext Scientist
May 2025 — Present · Cambridge, MA, US
Discovery pharmaceutics function, Chemical and Pharmaceutical Profiling (CPP), and contribute to the development of discovery compounds in collaborative research environment working as part of cross functional drug discovery teams in providing a developability assessment of new chemical entities. Working independently to execute pre-formulation activities for small molecule and oligonucleotide drug candidates. As such, strong competency in physical pharmacy and preclinical formulation development is preffered to efficiently function in this role and in understanding the physicochemical properties of new chemical entities and implementing formulation strategies to maximize the exposure in preclinical in vivo studies-Design and develop stage appropriate, fit-for-purpose preclinical formulations. This includes development of both oral and parenteral formulations on a small scale• Screening of solubility and dissolution rate enhancing formulations such as nanosuspensions and amorphous solid dispersions• Assessment of the performance of prototype formulations using in vitro tests such as dissolution, precipitation behavior, and stability• Basic drug substance characterization by techniques such as XRPD, DSC and TGA, DVS, PLM, DLS and UPLC. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability• Preparation of formulations for use in preclinical in vivo studies and authoring protocols describing preparation of formulations for use at internal and external formulation labs• Routine lab support such as buffer and mobile phase preparation, pH meter calibration, and basic troubleshooting of lab equipment. Shipping and receiving of samples between other Novartis and external sites
Education
University of Massachusetts Amherst
Biology, General
Holyoke Community College
Associate's degree, Biology, General
2014 — 2016
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