Tihomir Dodev

Senior Research Scientist @Spur Therapeutics

London, GB
MOBILE NUMBERS
+91 *********19

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WORK HISTORY

Sep 2016 — Present

Senior Research Scientist @Spur Therapeutics

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EDUCATION

2005 — 2008

Università degli Studi di Perugia

BSc, Biotechnology

2009 — 2012

King's College London

Doctor of Philosophy (Ph.D.), Molecular Biology

SKILLS

PcrImmunofluorescenceSingle Cell CloningCellPurificationProtein ExpressionSingle Cell AnalysisResearchCell BiologyAntibodiesMolecular CloningRt-PcrScienceTissue CultureColumn ChromatographyDnaMonoclonal AntibodiesImmunoglobulin Repertoire AnalysisTransfectionDna SequencingLife SciencesWestern BlottingHplcHigh Throughput ScreeningMolecular BiologyExpression CloningSds-PageElectrophoresisAffinity ChromatographyLaboratoryProtein PurificationDna ExtractionRna IsolationElisaCell CulturePrimary Cell IsolationImmunoprecipitation

ABOUT TIHOMIR DODEV

PhD-qualified, self-directed and highly collaborative molecular biologist with 11 years’ experience in discovery, production and validation of antibody therapeutics. Following a BSc in biotechnology I completed a PhD in Molecular Biology, focusing on the development of an antibody cloning and expression system, facilitating high-throughput screening and validation of novel allergen-specific and antitumor antibodies, providing bioanalytical support for radiolabelling and biodistribution studies in early antibody discovery programs in oncology and inflammation. Utilizing the antibody production platform, I conducted postdoctoral studies investigating age-related changes of the antibody repertoire using Next Generation Sequencing. I have innovative experience working in cross-functional teams, and the ability to drive projects and manage resources. Additional expertise includes- Fc-fused antigen and Fab cloning and production - V(D)J library preparation and HTS data analysis of immunoglobulin genes - Experimental and analytical method design and development - Strategies for high throughput screening assays

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Tihomir Dodev — Senior Research Scientist at Spur Therapeutics in London, GB | Unifers