Tiernan O.
Clinical Biomarkers | Translational Human Biology | Drug Discovery and Development
- Role
- Senior Director, Head of Translational Medicine and Clinical Biomarkers at Prime Medicine, Inc.
- Location
- Cambridge, MA, US
- LinkedIn followers
- 500 followers
About Tiernan O.
With over 15 years of research experience and a Ph.D. in Biochemistry, I have a strong background and passion for medicine creation, translational biology, biomarker discovery, and clinical development.
Experience
Senior Director, Head of Translational Medicine and Clinical Biomarkers
Jun 2025 — Present
In this role, I lead the translational medicine and clinical biomarker function, setting strategy across programs to connect preclinical and human biology with early clinical development. I oversee biomarker and clinical pharmacology approaches that support dose selection, proof-of-mechanism, and development decisions, and partner closely with research, clinical, regulatory, and external collaborators to ensure translational rigor and alignment from IND through early clinical studies.
Education
University of Regensburg
Socrates student, Medicinal Chemistry
University College Dublin
Ph.D, Biochemistry
Harvard Medical School
Research Fellow, Neurology
Harvard Medical School
Postdoctoral Research Fellow, Neurology
University of Galway
M.Sc, Neuropharmacology
Trinity College Dublin
B.A. mod., Medicinal Chemistry
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