John Hughes

WORK HISTORY

EDUCATION

SKILLS

ABOUT JOHN HUGHES

An accomplished and innovative top operations leader with extensive experience in the molecular biology and diagnostics markets, as well as in operations analysis, product development, Lean operations, Six Sigma, Kaizen, process improvement/development, customer relations, and strategic planning. I create and develop high performance teams that consistently deliver top and bottom line business growth by reducing costs, and increasing company profitability.Leadership andManagement:• Drove 7% increase in Services Business volume in flat market while increasing gross margin by 36 percentage points • Achieved greater than 8% reduction in cost through application of Lean and Six Sigma tools, resulting in annual savings • Demonstrated expertise in creating organizations, optimizing operational efficiency, and multi-site management• Exceeded company metrics in mentoring, developing and retaining individuals and team members• Maintained top 5% in all managerial effectiveness evaluations• Established strong customer relationship focus with large diagnostic business partners, key service customers, and Department of DefenseTechnicalAchievement: • Developed cGMP processes and facility design• Invented key proprietary processes including novel, automated large-scale purification process, saving over annually• Lead role in establishing a multi-million dollar product line in key market–developed antibodies, purification process, and analytical assays for Platinum®Taq DNA polymerase• Developed the purification process for a multi-million dollar product platform–SuperScript® Reverse Transcriptase• Responsible for a direct cost reduction of over annually by developing a patented purification process for Native Taq DNA polymerase• Developed over 30 enzyme products for the molecular biology, diagnostics and oncology markets• In-depth experience in fermentation and cell culture• 6 patents, 9 publicationsSpecialties: Enzymology, Assay Development, Organic chemistry, Fermentation, DOE, TFF, Project management, Cell Culture, Life Science service management, Large-scale protein and nucleic acid process development, cGMP, Business management, Lean, Six Sigma, and ERP systems, High Performance Work Teams, In vitro diagnostics, molecular diagnostics.