Sumit Mukherjee

About Sumit Mukherjee

I am a preclinical oncology R&D leader with 13+ years of research experience and 3+ years in biotech, advancing therapeutic programs from target validation through IND-enabling studies. I currently lead in vivo biology and translational pharmacology for a multi-asset oncology pipeline, supporting decision-making across discovery, development, and clinical transition.My work spans solid tumors and hematologic malignancies, with deep expertise in in vivo efficacy, mechanism-of-action, resistance biology, and rational combination strategies. I collaborate closely with Clinical, Business Development, and CMC teams to generate decision-quality preclinical data that informs portfolio prioritization, stage-gate advancement, and patient-selection strategy.I manage and mentor scientific teams, oversee global academic and CRO partnerships, and maintain accountability for preclinical budgets and execution. I also support external scientific diligence and partner-facing discussions through development-ready data packages and scientific communication.I am a highly cited scientist (20+ peer-reviewed publications;>1200 citations; h-index 14), including a Science Translational Medicine issue cover article. My recent work has been presented at AACR, SABCS, SITC, AACR–NCI–EORTC, and SNMMI, and I also has contributed to multiple competitive funding awards from the Mark Foundation, U.S. Department of Defense, and the National Cancer Institute.I am passionate about building rigorous, translationally relevant preclinical strategies that accelerate high-impact oncology medicines from concept to clinic.

Experience

1. Manager of in Vivo Biology

   Actinium Pharmaceuticals, Inc.

   Jan 2025 — Present · New York, NY, US

   Lead in vivo pharmacology and translational biology for a multi-asset oncology pipeline across solid tumors and hematologic malignancies.• Drive efficacy, MOA, resistance, and combination strategies to inform clinical positioning and IND-enabling decisions.• Partner with Discovery, Clinical, Regulatory, and CMC teams on preclinical strategy and development readiness.• Manage and mentor scientists; oversee CRO execution and preclinical budgets.• Present data internally and externally; support scientific diligence and conference communications.• See Publications section for representative peer-reviewed articles.

Education

• The West Bengal University of Health Sciences, Kolkata

  Master of Science (M.S.), Biotechnology

  2009 — 2011

• University of Calcutta

  Bachelor of Science (B.S.), Zoology/Animal Biology

  2005 — 2008

• The Graduate Center, City University of New York

  Doctor of Philosophy (PhD), Biochemistry

  2012 — 2018