Srinivasa Cheruku
Vice President, Medicinal Chemistry @Chemveda Life Sciences India
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WORK HISTORY
Vice President, Medicinal Chemistry @Chemveda Life Sciences India
US
EDUCATION
MIT Sloan School of Management
EXECUTIVE CERTIFICATE IN TECHNOLOGY AND OPERATIONS
Nizam College, Hyderabad,Telangana
Master’s Degree, Organic Chemistry
National Tsing Hua University
Postdoctoral, Medicinal chemistry
Université Paris Cité
Indo-French Postdoctoral Fellow, Medicinal chemistry
University of Nebraska Medical Center
Postdoctoral, Medicinal chemistry
North-Eastern Hill University
Ph.D., Organic Chemistry
SKILLS
ABOUT SRINIVASA CHERUKU
PhD-level experienced synthetic/medicinal chemist and accomplished technical Project Leader with a proven track record of developing small molecule-based products (drugs, dyes, performance materials). Synthesis: Multi-step synthesis of small molecules, peptides, oligonucleotides, polymers, natural products, and dyes. Design of synthetic routes, feasibility assessments, timeline estimation, raw material (chemical/reagent sourcing), and scale-up process optimization. Bio-conjugations, radio- and fluorescent labeling techniques. Process and API scale ups: Experience in drug substance conceiving synthetic routes and process development, analytical method development and validation, tech transfer, and cGMP manufacture. Demonstrated success of formulation development of poorly soluble APIs. Excellent track record of achieving corporate goals within budget and project timelines through strategic development and tactical execution with CMO/CRO partners and cross-functional collaboration. Proficient in CMC such as global regulatory submissions, regulatory starting material justification and ICH M7 compliance.Medicinal chemistry: Contributed in one approved malaria drug and multiple clinical candidates. Multiple therapeutic areas (Anticancer, anti-infectious, cardiovascular, autoimmune and CNS). Target design by structure/fragment-based, computer-aided, HTS and scaffold-hopping. SAR analysis of in vitro pharmacology and in vivo ADMET.Programs Management: Project Leadership, client relations and engagement, support to business development & marketing teams for lead generation, grant writing, IP liaison, team leadership, supervision, and cross-functional collaborations- Gained knowledge and experience in applying green chemistry principles to design nontoxic sustainable processes for molecules with applications in dyes, drugs, polymers, performance materials (fuel additives, coatings), micro-encapsulation, micelles or emulsifiers, nanoparticles)- Co-authored in 40 patents/publications (19), and presentations (6).
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