Soma Mandal

About Soma Mandal

Authorized to work for any US employer, visa sponsorship not required\"Experience in: small-molecule therapeutics, mechanism of action determination, Protein-ligand interaction, SAR analysis, structure-based design, protein: expression, purification, assay development.Highly experienced biochemist/molecular biologist currently looking for opportunities. I have over a decade of research experience in drug discovery, target-based drug discovery, structure-activity-relation analysis, protein-ligand interaction, assay development, protein purification, and handling & growth of a wide array of microorganisms. I have also determined the mechanism of action of small molecule bacterial inhibitors, using multiple experimental and data analysis approach. Experience in using MOE to analyze protein structure, protein-ligand interaction, protein engineering, and antibody engineering.• Identification and characterization of functional cellular binding targets inside bacterial RNA Polymerase. • Discovery of novel antituberculosis agents.(mycobacterial RNA Polymerase inhibitors)• Systematic lead optimization (in vitro screening).

Experience

1. Lead Scientist

   Inventprise

   Jan 2021 — Present · Redmond, WA, US

   Inventprise, Inc. — Lead Scientist• Built and led a novel vaccine device (combination) manufacturing platform from concept to ground-up; designed for low-cost commercial scalability and operational robustness.• Delivered key stage-gate outcomes and advanced the program from $500K to $5M+/year investment through milestone execution and stakeholder alignment.• Owned end-to-end technical strategy: lab buildout, workflow design, process development, and analytics—operating with minimal internal precedent and constrained resources.• Led formulation and process development to meet TPP requirements (thermostability, dissolvability, dose delivery) and defined analytical QC assay strategy.• Developed a fluorescence + image-cytometry virus activity assay to improve throughput and decision-making speed; enabled rapid iteration during development cycles.• Primary interface for external partnerships: identified collaborators, created study plans/experimental designs, managed licenses and import/export documentation, and presented updates to stakeholders, managed product regulatory compliance collaborations.

Education

• Qwen

  Bachelor's degree, Chemistry

  2001 — 2004

• Rutgers University

  Doctor of Philosophy - PhD, Biochemistry, Biophysics and Molecular Biology

  2010 — 2013

• University of Calcutta

  Master's degree, Biochemistry

  2004 — 2006

• Rutgers University

  Graduate assistant, Biochemistry and Molecular Biology

  2006 — 2010

Skills

• Cell Culture
• Molecular Cloning
• Biochemistry
• Protein Purification
• Protein Chemistry
• In Vitro
• Molecular Biology
• Biomarker Discovery
• Elisa
• Cell Biology
• Drug Development
• Protein Expression
• Western Blotting
• Pcr
• Structural Biology