Sobhana A. S.
Ph.D., Chemical Engineering | GTx Bioprocess Technology Development | Alexion, AstraZeneca Rare Disease
- Role
- Senior Engineer at Alexion Pharmaceuticals, Inc.
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
About Sobhana A. S.
Interests and Core Competencies- 7+ years of research (industry and academic) experience in biopharmaceuticals - Bioprocess unit operation execution (ATF bioreactors, chromatography, UFDF etc.) in batch and continuous modes- Mammalian and microbial cell culture, transient transfection and transduction- Multi-format protein, viral vector and EV purification process development- Process Analytical Technology development and evaluation (spectroscopic tools, 2D-LC systems, microfluidics)- Multiplexed, high-throughput, combinatorial approaches for peptide synthesis and analysis- Characterization of process-related and product-related impurities, related biophysical characterization- Statistical methods for critical parameter identification, process optimization- Bio/cheminformatics methods and big data analyses for sequence-based property determination of peptides and proteinsStrengths- Proactive about science sharing and K-12 STEM advocate- Independent contributions and teamwork across functional domains- Servant leadership, peer mentorship, organized
Experience
Senior Engineer
Jan 2025 — Present · Boston, MA, US
Product Development for Genomic Medicines at Alexion, AstraZeneca Rare Disease- Early-stage Process Development for Viral Vector Gene Therapies- Drug Substance Scale-up and Tech Transfer- High-Throughput Methods and Next-Generation Technology Development- CMC Leadership and Scientific Literature Authorship
Education
Jawaharlal Nehru Technological University
Bachelor of Technology - BTech, Engineering in Biotechnology
North Carolina State University
Master of Science - MS, Chemical Engineering
North Carolina State University
Doctor of Philosophy - PhD, Chemical Engineering
New York University
Master of Science - MS, Biotechnology
Skills
- Computational Biology
- Purification
- Jmp
- Creative Writing
- Total Quality Management
- Technical Documentation
- Public Relations
- Troubleshooting
- Biochemistry
- Technical Data Analysis
- Cell Culture
- Bioinformatics
- Project Management
- Elisa
- Protein Chemistry
- Biotechnology
- Protein Purification
- Microsoft Office
- Animal Models
- Polymerase Chain Reaction (Pcr)
- Molecular Biology
- Public Speaking
- Sds-Page
- Genetic Engineering
- Microbiology
- Powerpoint
- Microsoft Excel
- C
- Project Planning
- Western Blotting
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