Simran Sarna
Undergraduate Research Assistant - Borrelli Lab @Uc Irvine School Of Medicine
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WORK HISTORY
Undergraduate Research Assistant - Borrelli Lab @Uc Irvine School Of Medicine
Irvine, CA, US
Completed a one-year research project examining isoform-specific roles of dopamine D2 receptors (D2L and D2S) in amphetamine-induced behaviors and synaptic plasticity- Investigated the effects of D2 receptor loss in indirect pathway medium spiny neurons (iMSNs) on addiction-related phenotypes and striatal signaling- Performed immunofluorescence staining, western blotting, PCR, and brain sectioning on genetically modified mouse models- Assisted with behavioral assays including Y-maze, Novel Object Recognition (NOR), and Elevated Plus Maze (EPM)- Presented findings at the 2025 UROP Symposium and completed the UCI Excellence in Research Program- 2024–2025 UROP Fellow; published in the UCI Journal of Undergraduate Research in the Biological Sciences- Currently conducting a follow-up project on D2L and D2S isoforms in the prefrontal cortex, focusing on their roles in cognition and synaptic function
EDUCATION
UC Irvine
Bachelor of Science - BS, Neurobiology and Behavior
South Torrance High School
High School Diploma
ABOUT SIMRAN SARNA
Hi! My name is Simran Sarna and I’m an undergraduate student at the University of California, Irvine majoring in Neurobiology. I’m passionate about bridging neuroscience, medicine, and service to better understand how biological and social factors shape health. Over the past few years, I’ve developed a deep appreciation for the human side of science, whether it’s through asking research questions in the lab or engaging with patients in clinical spaces. I’m especially drawn to the ways in which education, empathy, and advocacy can intersect to make a lasting impact. Looking ahead, I hope to pursue a career in medicine as a physician that integrates clinical care, research, and community outreach to support underserved populations and promote equitable health outcomes. I’m currently seeking meaningful clinical opportunities to further explore this path and continue growing as a future healthcare professional.
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