Sienna Butterfield
Clinical Trial Document Reviewer @Leeds Teaching Hospitals NHS Trust
Signup · Get unlimited contacts
WORK HISTORY
Clinical Trial Document Reviewer @Leeds Teaching Hospitals NHS Trust
Reviewed patient documents for Phase 1b cancer trial to enhance patient experience and understanding• Contributed to a PPIE report used by the sponsor, ethics committees, and research teams
EDUCATION
University of York
PhD, Biotechnology
Durham University
MSci in Natural Sciences, Biology & Chemistry
ABOUT SIENNA BUTTERFIELD
PROFESSIONAL SUMMARY• Biotechnology PhD holder and current Research Associate at the University of York in collaboration with FUJIFILM Biotechnologies. • Interested in biotechnology, innovation and the patent landscape with a passion for communicating complex science to varied audiences. EDUCATIONPhD in Biotechnology • My research surrounds epigenetic engineering approaches to improve the industrial production of biologics synthesised in mammalian cells. • I have investigated and manipulated epigenetic control of transgene expression to establish causal relationships. • Related publications can be accessed below.MSci Natural Sciences at Durham University • My MSci project synthesised and tested novel low molecular weight antibiotic compounds under the supervision of Dr. John Sanderson and Dr. Gary Sharples • A manuscript of this work is currently under preparationEXPERIENCEFreelance Medical Writer • I have completed projects under the Aspirations scheme by Aspire Scientific, creating deliverables which summarised and analysed data from research studies and clinical trails. Graduate Teaching Assistant • I have designed and delivered tutorials to undergraduate students, taught bioinformatics, mentored 20+ final year project students and assisted staff in lab, coding and Q&A sessions. Outreach Projects • I am involved in scientific outreach projects in the community including designing and delivering lectures on sustainability in biotech, presenting practical experiments to primary school children and organising the Pint of Science festival to engage the local community. PUBLICATIONS• Butterfield, S. P, Saunders, F. L, & White, R. J.(2025). Pioneer Factor FOXA1 Boost CHO Cell Productivity. Biotechnology Journal 21 (1): e70171. • Butterfield, S. P, Sizer, R. E, Saunders, F. L, & White, R. J.(2024). Selective Recruitment of a Synthetic Histone Acetyltransferase Can Boost CHO Cell Productivity. Biotechnology Journal, 19(12), e20•••••74. • Sizer, R. E, Butterfield, S. P, Hancocks, L. A, De Sousa, L. G, & White, R. J.(2024). Selective Occupation by E2F and RB of Loci Expressed by RNA Polymerase Cancers, 16(3), 481. • Butterfield, S. P, Sizer, R. E, Rand, E, & White, R. J.(2023). Selection of tRNA Genes in Human Breast Tumours Varies Substantially between Individuals. Cancers, 15(14). https://doi.org/10.3390/cancers15••••76 • Sizer, R. E, Chahid, N, Butterfield, S. P, Donze, D, Bryant, N. J, & White, R. J.(2022). Chromatin Insulators Through Eukaryotic Evolution. Gene, 835, 146533.
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.