Shesh Sharma

About Shesh Sharma

Shesh is a seasoned operations executive and management consultant with deep experience transforming organizations and scaling operations in high-growth startups and Fortune 100 Biotech and Cell & Gene Therapy (CGT) companies. Over the past decade, he has led early- and late-stage CGT organizations—spanning autologous, allogeneic, and iNK (iPSC) platforms—through transformative change from early development to commercial readiness and launch.Shesh is a trusted partner to executive teams on operations strategy, organization design, manufacturing readiness, and productivity improvements. He has architected and built global operations ecosystems—spanning end-end supply chain, manufacturing, and tech-enabled infrastructure— and led phase-appropriate lifecycle transitions while delivering value through operational excellence, cost efficiency, and organizational agility. A strong communicator, he is known for influencing strategic decision-making in complex, highly matrixed organizations. Shesh has played a pivotal role in shaping early-stage CGT ventures—partnering with founders, developing investor-facing value propositions, supporting fundraising, and designing execution-ready growth strategies. He brings a visionary perspective—connecting operational capabilities with strategic goals to position companies for long-term success in complex, regulated markets.Widely recognized as a thought leader in biotech operations, Shesh has published insights on the commercialization challenges of cell and gene therapy (CGT) products and recently contributed to an industry consortium on “Strategic Sourcing for Productivity, Quality, Resilience, and Sustainability.” He has also contributed to research on biotech board composition, governance, and its influence on firm performance. Earlier in his career, Shesh held leadership roles at top-tier consulting firms, including Kearney and PwC.

Experience

1. Management Consultant

   Arsenal Biosciences, Inc.

   Apr 2024 — Present

   Multiple projects covering operations strategy and scale-up - supply chain, direct material sourcing, patient journey, apheresis center & patient logistics, operations excellence, and metrics.

Skills

• Supply Chain Management
• Strategic Sourcing
• Business Analysis
• Procurement
• Vendor Management
• Product Management
• Project Management
• Business Process Improvement
• Sourcing
• Supply Chain
• Cross-Functional Team Leadership
• Change Management
• Strategic Planning
• Management Consulting
• Business Strategy
• Strategy
• Outsourcing
• Process Improvement
• Start-Ups