Sharon Lin
- Role
- Principal Scientist at Ksq Therapeutics, Inc
- Location
- Arlington, MA, US
- LinkedIn followers
- 500 followers
About Sharon Lin
As a Principal Scientist at KSQ Therapeutics, I lead the development of CRISPR engineered…
Experience
Principal Scientist
Aug 2021 — Present
Involved in decision making IND enabling studies for CRISPR enginered TIL cell therapy - Oversee and enable execution of all non-clinical activities including in vitro pharmacology and genotox safety for IND enabling studies- Secondary manager, manage a team of 3~4 - Cross-functional collaboration with in vivo team for IND enabling safety studies and MOA studies - Cross-functional collaboration with analytical development team and quality team for release assay development - Cross-functional collaboration with process development team and CMC team for process tech transfer
Skills
- T Cells Stimulation and Expansion
- Fluorescence Microscopy
- Akta System
- Facs
- Atpase Assay
- High Throughput Fortessa
- Protein Crystal Preparation
- Pcr
- Insect Cell Culture (Sf9)
- Biochemistry
- Western Blot
- Crispr
- Vector Nti Program
- Dna Fiber Assay
- Elisa
- Gel Shift Assay
- Dna Sequencing Gel
- Western Blotting
- Mammalian Cell Transfection (Both Plasmid and Rnai)
- Qpcr
- Protein Purification
- Transfection
- Molecular Cloning
- Molecular Biology
- Immunofluoresce Microscopy
- Mtt Assay
- Tca Precipitation
- Lentivirus Production
- Poly Da Oligo Dt Assay
- Two-Dimensional Electrophoresis
- In Vitro
- Cell Culture
- Rt-Pcr
- Lsrii
- Recombinant Protein Purification
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