Shao Ning Y.

About Shao Ning Y.

SUMMARY: 20 years of research experience. • 15 years of experience working with mouse models • 13 years working with mouse syngeneic and xenogeneic tumor model • 15 years of assay development and testing experience in cancer research • 4 years of in vitro T cell activation assay development in I/O setting • 8 years of experience in high throughput screening of small molecules • Contributed to the identification of several novel lymphoma therapies, including a B-Cell Lymphoma 6 (BCL6) peptide inhibitor and Heat Shock Protein 90 (HSP90) inhibitor and BRAF inhibitor in Phase I clinical trials • Collaborated with international pharmaceutical companies for new compound testing in Diffuse Large B Cell Lymphoma (DLBCL) • Contributed to 24 publications, including Nature Medicine, Nature Communications, Cancer Cell, Journal of Clinical Investigation, PLOS One and Cancer Discovery • Set up and optimized laboratory workflow while overseeing students and technicians, as lab manager of a newly established lab

Experience

1. Scientist

   Regeneron

   Nov 2023 — Present · Tarrytown, NY, US

   Validating target variants using transient transfection• Developing cell-based dimerization assays for multiple targets• Validating target expression with using flowcytometry Key techniques implemented: Cell culture, mini-prep, transient transfection, reporter assay, sanger sequencing, chemical induced dimerization assay

Education

• National Taiwan University

  Master, Immunology

  1998 — 2000

• National Central University

  BS, Biochemistry

  1993 — 1998