Serkan Erdin
Director of Bioinformatics @Massachusetts General Hospital
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WORK HISTORY
Director of Bioinformatics @Massachusetts General Hospital
Boston, MA, US
Overseeing and coordinating bioinformatics activities of Genomics & Technology Core (GTC).Co-leading computational functional genomics team of 6 researchers in the Talkowski laboratory, overseeing and coordinating project strategy, data analysis, and collaborations with other academic labs and industry partners. Leading computational and statistical analyses of transcriptomic and epigenetic datasets to uncover convergence and functionally characterize Autism Spectrum Disorder(ASD)/neurodevelopmental disorders(NDD)-associated genes and copy number variations, as well as conducting in-depth functional genomic analysis of cohesin complex genes. Engaged in computational and statistical analyses of multi-omics data – including genomics, epigenetics, proteomics, and transcriptomics – in the context of various neurogenetic disorders such as ASD/NDD, Prader-Willi Syndrome(PWS), Tuberous Sclerosis Complex(TSC) and X-linked dystonia-parkinsonism(XDP) in collaboration with faculty members at the Massachusetts General Hospital (MGH) and the Broad Institute as well as research teams at institutions across the United States.
EDUCATION
Boğaziçi University
M.S., Physics
Texas A&M University
Ph.D, Physics
Boğaziçi University
B.S., Physics
SKILLS
ABOUT SERKAN ERDIN
I am director of bioinformatics at the Center for Genomic Medicine at Massachusetts General Hospital (MGH) with over 15 year research experience in life sciences. I am also affiliated with the Broad Institute of MIT and Harvard as an associated scientist. My work centers on the development and application of computational and statistical approaches to study genomic, epigenetic and transcriptomic data, with a particular focus on neurogenetics and molecular mechanisms underlying neurogenetic disorders such as autism spectrum disorder, Huntington\'s disease, neurofibromatosis, Pradir-Willi syndrome and X-linked dystonia parkinsonism. Prior to this role, I was a staff research scientist and group leader in computational functional genomics at MGH. Before joining MGH, I worked as a bioinformatics consultant at Computational and Integrative Biomedical Research Center and as a postdoctoral fellow at the Department of Molecular and Human Genetics at Baylor College of Medicine, where I investigated protein function-structure relationships and chromatin function. I earned my Ph.D. in theoretical physics from Texas A&M University and pursued my initial research endeavors in computational and physical chemistry at the University of Minnesota and Argonne National Laboratory. Specialties: Computational biology, bioinformatics, genomic data science, functional genomics, neurogenetics, next-generation sequencing, next-generation sequencing, bulk and single RNA-seq, miRNA-seq, whole-exome and genome sequencing, ChIP-seq, ATAC-seq, chromosome conformation capture (HiC), statistical modeling, machine learning, comparative protein sequence and structure analysis, protein sequence-structure-function relationships, and neurodevelopmental and neurodegenerative disorders.
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