Sebastian Thomas

About Sebastian Thomas

I love to be an eccentric outlier in a world that\'s confined by Mean +/- 3 SD\". A strong believer in one\'s work should reflect oneself. I\'m open to Lead/Principal statistician roles (both professional & academia) that is primarily focused on a steep learning curve, challenging tasks, methodology development and its application to different studies. For conducting academic sessions/key opportunities, kindly drop a mail to s••••••••@gmail.com. 1⃣ A dynamic, open-minded research professional and an organized statistician with 5+ years of research experience in the areas of: 1. Phase-1 dose escalation studies, PK/PD modelling in oncology studies2. Frequentist and Bayesian modelling3. Advanced Non-Parametric Inference for handling composite endpoints 4. Analysis of Clinical Outcome Assessments (COA) endpoints5. Pure Mathematics, Applied Statistics, Multilevel modelling, Econometrics and interest in learning Pathophysiology.2⃣ Worked on multiple regulatory submissions and deliverables at a faster submission rate with no compromise on data quality. Trial Statistician for the first and only functional outcomes trial in Novo Nordisk. Reviewer of internal submissions with an excellent record of positive regulatory response.Tasks involved: Trial submissions to HA, Methodology development, Multiple exploratory tasks, knowledge sharing of Bayesian and other stat techniques, Q&A by both regulatory and stakeholders, safety signal requests, PSUR/DSUR, Creation of dynamic programs for stat methods and complex TLF\'s using SAS/R.3⃣ Skilled in developing Novel Frequentist and Bayesian Adaptive designs for Phase-1 dose escalation studies, conduct of statistical analysis, sample size calculations, Design and Analysis of Clinical Experiments and reporting backed by training in R (Intermediate), SAS (Intermediate) and WINBUGS (Advanced). Proficient in the creation of CDISC compliant ADaM and AX datasets.4⃣ Research Area: Modelling of Maximum Tolerated Dose (MTD) of early Phase 1 studies via developing a novel \"Color Code Scheme\" and \"Sequential\" Frequentist and Response Adaptive Bayesian techniques. This paper has been presented in 30+ national and international conferences including PHUSE Webinar (2023), PHUSE EMEA SDE Heidelberg (2022), CONSPIC IASCT, ISCR etc.5⃣ When I\'m not working, I\'m likely to involve myself in art and sports. Listening to Indian Classical Music (Singing), writing dark short stories, abstract painting and playing badminton are some of my interests.

Experience

1. Associate Senior Statistician

   Novo Nordisk

   Sep 2025 — Present · Bangalore Urban, IN

Education

• Christ School

  Class 10 (Secondary School Leaving Certificate)

  2003 — 2015

• Christ University, Bangalore

  Pre-University(Class11&12), Physics, Chemistry, Mathematics, Biology

  2015 — 2017

• St Joseph's University

  Bachelor of Science - BSc, Economics, Mathematics and Statistics

  2017 — 2020

• Manipal Academy of Higher Education

  Master of Science - MS, Biostatistics

  2020 — 2022