Anagha S.
Principal Scientist | Rare Diseases | AAV gene therapy | Obesity
- Role
- Principal Scientist at Flagship Pioneering
- Location
- Arlington, MA, US
- LinkedIn followers
- 500 followers
About Anagha S.
Highly motivated independent scientist with 10+ years of industry experience working in preclinical discovery for small molecules, biologicals, AAV-based gene therapy modalities in rare hematology, cardiac and neurological indications.• Extensive expertise and experience in:o Building cellular assays using immortalized and primary cells, for screening and evaluating efficacy of therapeutic modalitieso Establishing complex primary cellular models of disease in-house, including iPSC-derived neurons, cardiomyocytes, intestinal epithelial cells and primary bronchial epithelial cellso Contributing to multiple projects simultaneously in a fast-paced, highly matrixed research environment with a proven track record of providing key decision-making data setso Conceptualizing and executing experiments independently, as well as coordinating with vendors, CROs and partner lineso Molecular biology, including but not limited to DNA and RNA analyses (ddPCR, qPCR, splicing analysis), FACS, western blot, cell transfection and viral transduction, siRNA, CRISPR, cloning, ELISA.
Experience
Principal Scientist
Oct 2025 — Present · Cambridge, MA, US
Education
Northeastern University
Master of Science, Pharmacology
2010 — 2012
University of Mumbai
B.Pharm, Pharmacy
2005 — 2009
Skills
- Assay Development
- Microscopy
- Protein Expression
- Cell Culture
- Pbmc Isolation
- Gene Therapy
- Cytotoxicity
- Recombinant Dna Technology
- Cell Biology
- Stem Cells
- Luciferase Assay
- Viral Vectors
- Dna Sequencing
- Ddpcr
- Aav
- Molecular Biology
- Immunohistochemistry
- Qpcr
- Immunoassays
- Pcr
- Taqman
- Western Blotting
- Molecular Cloning
- Cell Based Assays
- Flow Cytometry
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