Samhita Mahapatra

About Samhita Mahapatra

Bioprocess scientist and team lead with proven experience in upstream fermentation…

Experience

1. Senior Scientist

   Raspa

   Oct 2023 — Present · Lucknow, IN

   Led the design and execution of upstream fermentation process development for two high-value small-molecule APIs, focusing on immunosuppressant production and process improvement through strategic media optimization, seed train refinement, and advanced mutagenesis with high-throughput screening.• Maintained high sterility compliance across all aseptic handling operations through rigorous technique and procedural discipline, with a strong record of sterility assurance and operational reliability; developed a high-throughput screening platform for efficient strain selection, accelerating candidate identification and boosting productivity.• Authored and reviewed extensive SOPs and technical reports, driving a sharp decline in deviation incidents and standardizing key workflows, including media preparation, daily operations, and equipment handling—supporting robust compliance.• Maintained robust inoculum sterility across bioreactor and shake flask operations through diligent aseptic practices and process monitoring—ensuring process consistency and product quality; contributed to the development and optimization of multiple ICH-aligned HPLC methods, enhancing analytical throughput and reducing runtime.• Managed a cross-functional R&D team, streamlining task delegation and project tracking using tools like Trello and Slack—significantly improving internal collaboration and workflow visibility.