Rodrigo dos Santos Chaves
Senior Scientist @Ionis Pharmaceuticals, Inc.
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WORK HISTORY
Senior Scientist @Ionis Pharmaceuticals, Inc.
Carlsbad, CA, US
Developed and optimized a platform to enable employing hIPSC-derived patient neurons in the development of oligonucleotide therapeutics candidates for patients with ultrarare/n of 1 diseases- Interrogated patients\' genomic data to identify novel target sites for oligonucleotide binding and assay design- Lead initiatives to identify and access tolerability/safety of novel oligonucleotide development candidates for multiple targets employing hIPSC-derived patient neurons.
EDUCATION
Universidade Metodista de São Paulo
Bachelor’s Degree, Biology/Biological Sciences, General
UC San Diego
Graduate Scholar, Stem Cells and Alzheimer's Disease
USP - Universidade de São Paulo
Doctor of Philosophy (Ph.D.), Experimental Physiopathology
ABOUT RODRIGO DOS SANTOS CHAVES
Highly skilled, accomplished, and innovative biomedical research scientist with 10+ years of experience designing and leading biomedical research projects applying stem cell technologies and genomic engineering tools to dissect complex physiopathological processes leading to neurodegenerative diseases, as evidenced by +11 publications in peer-reviewed journals. Exceptional public speaker and communicator as demonstrated by attending +12 conferences and presenting +30 abstracts. Excellent team player with strong leadership and mentoring skills to lead research projects as evidenced by mentoring 6+ students. Proficient in cellular, biochemical, and molecular biology technologies and tools including human induced pluripotent stem cell (hIPSC) culturing, neuron differentiation, cell sorting, GWAS-based study, CRISPR-mediated genomic editing, siRNA/shRNA, oligonucleotide high-throughput screenings, ELISA/MSD, gene cloning, transfections, and cell live imaging assays.
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