Renzo Perales

About Renzo Perales

Translational immunologist and senior/principal-level scientist with 10+ years advancing immune-based therapies from discovery to early clinical development. I lead biomarker strategy and fit-for-purpose assay development and validation across clinical-phase programs—building standardized, reproducible workflows that inform dose selection, patient response, and translational decision-making.My work spans T-cell biology, tumor microenvironment, and vaccine/cell therapy immunology, with deep expertise in multiparametric flow/ICS, ELISpot/ELISA (including multiplex platforms), potency and immunogenicity assays, and in vivo/ex vivo models. I’ve driven IND-supportive data packages, contributed to Investigator Brochures and FDA meeting responses, and partnered closely with Clinical Operations, Regulatory, Manufacturing, and CRO/CDMOs to deliver decision-grade translational data.Highlights include leading immune monitoring and biomarker discovery for personalized cancer vaccine trials (Nature Medicine 2024; Nature Cancer in press, 2026). Built and optimized T-cell functional assays and engineered patient-derived T-cell clones to elucidate mechanism of action and correlates of response. Mentored and grew teams, refined QC/QA processes, and created assay transfer frameworks that scale across sites.Interests: Immuno-oncology, vaccine immunology, cell & gene therapy; biomarker strategy; clinical assay deployment; CDx collaborations.Keywords: Translational Immunology, Immuno-Oncology, Biomarkers, Immunogenicity, Fit-for-Purpose Validation, IND/IB, Flow Cytometry/ICS, ELISpot/ELISA, T-cell Biology, Potency Assays, CRO/CDMO Oversight, CDx, Nature Medicine 2024.

Experience

1. Scientific Advisor

   Ozcorp Scientific

   Dec 2025 — Present

   Provide scientific guidance on study design, research direction, grant writing, and interpretation of immunological data across R&D and therapeutic development programs.

Education

• Universidad Peruana Cayetano Heredia

  Bachelor's degree, Biology, General

  2001 — 2005

• Drexel University College of Medicine

  Doctor of Philosophy (PhD), Microbiology and Immunology

  2010 — 2015

• University of Pennsylvania School of Medicine

  Postdoctoral Researcher, Cancer immunity, tumor evasion, immunotherapies and adaptive immunity

  2017 — 2020

• Children's Hospital of Philadelphia

  Postdoctoral Researcher, Antigen presentation (MHC class-I and –II), T cell biology and antiviral immunity

  2016 — 2017

Skills

• Teamwork
• Immunohistochemistry
• Qpcr
• Research
• Biochemistry
• Flow Cytometry
• Problem Solving
• Immunology
• Pcr
• Cell Culture
• Team Leadership
• Confocal Microscopy
• Microscopy
• Cell Biology
• Molecular Biology
• Fluorescence Microscopy
• Elisa
• Tissue Culture
• Rt-Pcr
• Project Planning
• Western Blotting
• Molecular Cloning
• Science
• Data Analysis
• Protein Purification
• Microbiology