Ray Unwalla

About Ray Unwalla

Senior Computational Chemist with extensive drug discovery experience and a proven track record of accomplishments in the area of Nuclear Hormone Receptor and Kinase. In depth knowledge of various computational tools and techniques to efficiently drive project goals. As part of a multi-disciplinary team, designed and optimized novel chemical entities and enabled effective application of computational tools to directly impact analogs synthesized by medicinal chemists. The computational analysis had a direct impact in the design of 2 Phase II candidates and several predevelopment candidates. Excellent medicinal chemistry insight, communication skills and a passion for drug discovery. Clear, effective written & communication skills, Good knowledge of CADD-related infrastructure and technology. Ability to work in a multi-disciplinary team environment with members of other teams. Specialties: In depth knowledge of techniques used in computer aided drug design with a strong background in computational chemistry. Expertise include structure based drug design, ADMET liability modeling. molecular dynamics, quantum mechanics, QSAR, virtual screening, pharmacophore generation, Data mining & HTS analysis. Experience in applying these techniques to design entites(small molecules/peptides/libraries) for Nuclear Hormone Receptor and kinase projects.

Experience

1. Sr Research Scientist

   Pfizer

   Jun 1996 — Present

   Senior Computationl Chemist: Site head for Collegevile site. Expertise in Ligand and Structure-based design in the area of Nuclear Hormone Receptors

Education

• Louisiana State University

  PhD, Physical Organic Chemsitry

  1980 — 1987