Randall Toy
Principal Scientist - Non Viral Delivery @Novo Nordisk
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WORK HISTORY
Principal Scientist - Non Viral Delivery @Novo Nordisk
Lexington, MA, US
Make decisions and recommendations for research strategy for platform development. • Design and interpret results from studies for drug screening and preclinical development.• Lead team to implement machine learning for formulation design.• Evaluate external technologies for formulation screening and nucleic acid delivery.• Coordinated setup of formulation lab, including automation saving 10+ hours of work weekly.• Led activities to improve team collaboration, feedback culture, and goal setting.
EDUCATION
Case Western Reserve University
Ph.D, Biomedical Engineering
University of Pennsylvania
BSE, Bioengineering, Minor in Economics
SKILLS
ABOUT RANDALL TOY
Scientific leader with over 11 years of experience with R&D for gene therapy. I make decisions and influence research strategy in the Nucleic Acid Research group at Novo Nordisk. In my role, I screen formulations for nucleic acid drugs and bring lead candidates through preclinical development. To accelerate research execution, I evaluate high-throughput screening technologies, build automated workflows, and lead the implementation of machine learning for formulation design. I have experience both as a project manager and a people manager.My primary technical expertise is in the formulation, characterization, and in vitro/in vivo screening of nanoparticles for drug delivery. I have worked with lipid nanoparticles (LNPs) and polymer nanoparticles that deliver siRNA, mRNA, DNA, or gene editors. I have worked on drugs for the eye, oncology, vaccines, hemophilia, and cardiometabolic disease. I have published 20 peer-reviewed manuscripts, 2 book chapters, and 5 patent applications. I am strongly motivated to advance cutting edge platform technologies into clinical development and aspire to be an enterprise leader in pharma/biotech.
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